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Repolarization of tumor infiltrating macrophages and increased survival in mouse primary CNS lymphom...

Repolarization of tumor infiltrating macrophages and increased survival in mouse primary CNS lymphom...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7452938

Repolarization of tumor infiltrating macrophages and increased survival in mouse primary CNS lymphomas after XPO1 and BTK inhibition

About this item

Full title

Repolarization of tumor infiltrating macrophages and increased survival in mouse primary CNS lymphomas after XPO1 and BTK inhibition

Publisher

New York: Springer US

Journal title

Journal of neuro-oncology, 2020-08, Vol.149 (1), p.13-25

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Background
Patients diagnosed with primary central nervous system lymphoma (PCNSL) often face dismal outcomes due to the limited availability of therapeutic options. PCNSL cells frequently have deregulated B-cell receptor (BCR) signaling, but clinical responses to its inhibition using ibrutinib have been brief. In this regard, blocking nuclear e...

Alternative Titles

Full title

Repolarization of tumor infiltrating macrophages and increased survival in mouse primary CNS lymphomas after XPO1 and BTK inhibition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7452938

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7452938

Other Identifiers

ISSN

0167-594X

E-ISSN

1573-7373

DOI

10.1007/s11060-020-03580-y

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