Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2
Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Virus entry is a multistep process. It initiates when the virus attaches to the host cell and ends when the viral contents reach the cytosol. Genetically unrelated viruses can subvert analogous subcellular mechanisms and use similar trafficking pathways for successful entry. Antiviral strategies targeting early steps of infection are therefore appe...
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Full title
Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7456157
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7456157
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.2007837117