Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice
Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice
About this item
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Author / Creator
Mock, Elliot D. , Mustafa, Mohammed , Gunduz-Cinar, Ozge , Cinar, Resat , Petrie, Gavin N. , Kantae, Vasudev , Di, Xinyu , Ogasawara, Daisuke , Varga, Zoltan V. , Paloczi, Janos , Miliano, Cristina , Donvito, Giulia , van Esbroeck, Annelot C. M. , van der Gracht, Anouk M. F. , Kotsogianni, Ioli , Park, Joshua K. , Martella, Andrea , van der Wel, Tom , Soethoudt, Marjolein , Jiang, Ming , Wendel, Tiemen J. , Janssen, Antonius P. A. , Bakker, Alexander T. , Donovan, Colleen M. , Castillo, Laura I. , Florea, Bogdan I. , Wat, Jesse , van den Hurk, Helma , Wittwer, Matthias , Grether, Uwe , Holmes, Andrew , van Boeckel, Constant A. A. , Hankemeier, Thomas , Cravatt, Benjamin F. , Buczynski, Matthew W. , Hill, Matthew N. , Pacher, Pal , Lichtman, Aron H. and van der Stelt, Mario
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
N
-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids. Using a high-throughput screen, chemical proteomics and targeted l...
Alternative Titles
Full title
Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice
Authors, Artists and Contributors
Author / Creator
Mustafa, Mohammed
Gunduz-Cinar, Ozge
Cinar, Resat
Petrie, Gavin N.
Kantae, Vasudev
Di, Xinyu
Ogasawara, Daisuke
Varga, Zoltan V.
Paloczi, Janos
Miliano, Cristina
Donvito, Giulia
van Esbroeck, Annelot C. M.
van der Gracht, Anouk M. F.
Kotsogianni, Ioli
Park, Joshua K.
Martella, Andrea
van der Wel, Tom
Soethoudt, Marjolein
Jiang, Ming
Wendel, Tiemen J.
Janssen, Antonius P. A.
Bakker, Alexander T.
Donovan, Colleen M.
Castillo, Laura I.
Florea, Bogdan I.
Wat, Jesse
van den Hurk, Helma
Wittwer, Matthias
Grether, Uwe
Holmes, Andrew
van Boeckel, Constant A. A.
Hankemeier, Thomas
Cravatt, Benjamin F.
Buczynski, Matthew W.
Hill, Matthew N.
Pacher, Pal
Lichtman, Aron H.
van der Stelt, Mario
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7468568
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7468568
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-020-0528-7
