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Pharmacologic fibroblast reprogramming into photoreceptors restores vision

Pharmacologic fibroblast reprogramming into photoreceptors restores vision

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7469946

Pharmacologic fibroblast reprogramming into photoreceptors restores vision

About this item

Full title

Pharmacologic fibroblast reprogramming into photoreceptors restores vision

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2020-05, Vol.581 (7806), p.83-88

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Photoreceptor loss is the final common endpoint in most retinopathies that lead to irreversible blindness, and there are no effective treatments to restore vision
1
,
2
. Chemical reprogramming of fibroblasts offers an opportunity to reverse vision loss; however, the generation of sensory neuronal subtypes such as photoreceptors remains...

Alternative Titles

Full title

Pharmacologic fibroblast reprogramming into photoreceptors restores vision

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7469946

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7469946

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-2201-4

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