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Gene of the month: TMPRSS2 (transmembrane serine protease 2)

Gene of the month: TMPRSS2 (transmembrane serine protease 2)

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7470178

Gene of the month: TMPRSS2 (transmembrane serine protease 2)

About this item

Full title

Gene of the month: TMPRSS2 (transmembrane serine protease 2)

Publisher

England: BMJ Publishing Group Ltd and Association of Clinical Pathologists

Journal title

Journal of clinical pathology, 2020-12, Vol.73 (12), p.773-776

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group Ltd and Association of Clinical Pathologists

More information

Scope and Contents

Contents

Transmembrane serine protease 2 is encoded by the TMPRSS2 gene. The gene is widely conserved and has two isoforms, both being autocatalytically activated from the inactive zymogen form. A fusion gene between the TMPRSS2 gene and ERG (erythroblast-specific-related gene), an oncogenic transcription factor, is the most common chromosomal aberration de...

Alternative Titles

Full title

Gene of the month: TMPRSS2 (transmembrane serine protease 2)

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7470178

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7470178

Other Identifiers

ISSN

0021-9746

E-ISSN

1472-4146

DOI

10.1136/jclinpath-2020-206987

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