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Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel u...

Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel u...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7471289

Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading

About this item

Full title

Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-09, Vol.10 (1), p.14559, Article 14559

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Suprabasin (SBSN) is expressed not only in epidermis but also in epithelial cells of the upper digestive tract where metals such as nickel are absorbed. We have recently shown that SBSN level is decreased in the
stratum corneum
and serum of atopic dermatitis (AD) patients, especially in intrinsic AD, which is characterized by metal allergy. B...

Alternative Titles

Full title

Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7471289

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7471289

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-71536-3

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