Aggravated ulcerative colitis caused by intestinal Metrnl deficiency is associated with reduced auto...
Aggravated ulcerative colitis caused by intestinal Metrnl deficiency is associated with reduced autophagy in epithelial cells
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Publisher
Singapore: Springer Singapore
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Language
English
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Publisher
Singapore: Springer Singapore
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Contents
Metrnl is a newly identified secreted protein highly expressed in the intestinal epithelium. This study aimed to explore the role and mechanism of intestinal epithelial Metrnl in ulcerative colitis. Metrnl
−/−
(intestinal epithelial cell-specific Metrnl knockout) mice did not display any phenotypes of colitis under basal conditions. However,...
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Full title
Aggravated ulcerative colitis caused by intestinal Metrnl deficiency is associated with reduced autophagy in epithelial cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7471395
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7471395
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ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/s41401-019-0343-4