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Defined microbiota transplant restores Th17/RORγt⁺ regulatory T cell balance in mice colonized with...

Defined microbiota transplant restores Th17/RORγt⁺ regulatory T cell balance in mice colonized with...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7474624

Defined microbiota transplant restores Th17/RORγt⁺ regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas

About this item

Full title

Defined microbiota transplant restores Th17/RORγt⁺ regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (35), p.21536-21545

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The building evidence for the contribution of microbiota to human disease has spurred an effort to develop therapies that target the gut microbiota. This is particularly evident in inflammatory bowel diseases (IBDs), where clinical trials of fecal microbiota transplantation have shown some efficacy. To aid the development of novel microbiota-target...

Alternative Titles

Full title

Defined microbiota transplant restores Th17/RORγt⁺ regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7474624

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7474624

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1922189117

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