Transport properties in CFTR−/− knockout piglets suggest normal airway surface liquid pH and enhance...
Transport properties in CFTR−/− knockout piglets suggest normal airway surface liquid pH and enhanced amiloride-sensitive Na+ absorption
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Previous analysis of CFTR-knockout (CFTR−/−) in piglets has provided important insights into the pathology of cystic fibrosis. However, controversies exist as to the true contribution of CFTR to the pH balance in airways and intestine. We therefore compared ion transport properties in newborn wild-type (CFTR+/+) and CFTR-knockout (CFTR−/− piglets)....
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Full title
Transport properties in CFTR−/− knockout piglets suggest normal airway surface liquid pH and enhanced amiloride-sensitive Na+ absorption
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7476968
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7476968
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ISSN
0031-6768
E-ISSN
1432-2013
DOI
10.1007/s00424-020-02440-y
