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Stopping transformed cancer cell growth by rigidity sensing

Stopping transformed cancer cell growth by rigidity sensing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7477912

Stopping transformed cancer cell growth by rigidity sensing

About this item

Full title

Stopping transformed cancer cell growth by rigidity sensing

Publisher

London: Nature Publishing Group UK

Journal title

Nature materials, 2020-02, Vol.19 (2), p.239-250

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A common feature of cancer cells is the alteration of kinases and biochemical signalling pathways enabling transformed growth on soft matrices, whereas cytoskeletal protein alterations are thought to be a secondary issue. However, we report here that cancer cells from different tissues can be toggled between transformed and rigidity-dependent growt...

Alternative Titles

Full title

Stopping transformed cancer cell growth by rigidity sensing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7477912

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7477912

Other Identifiers

ISSN

1476-1122

E-ISSN

1476-4660

DOI

10.1038/s41563-019-0507-0

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