IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon
IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The physiological stresses that diminish tissue stem-cell characteristics remain largely unknown. We previously reported that type I interferon (IFN), which is essential for host antiviral responses, is a physiological stressor for hematopoietic stem cells (HSCs) and small intestinal stem cells (ISCs) and that interferon regulatory factor-2 (IRF2),...
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IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7479133
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7479133
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-71633-3
