Telomere-to-telomere assembly of a complete human X chromosome
Telomere-to-telomere assembly of a complete human X chromosome
About this item
Full title
Author / Creator
Miga, Karen H. , Koren, Sergey , Rhie, Arang , Vollger, Mitchell R. , Gershman, Ariel , Bzikadze, Andrey , Brooks, Shelise , Howe, Edmund , Porubsky, David , Logsdon, Glennis A. , Schneider, Valerie A. , Potapova, Tamara , Wood, Jonathan , Chow, William , Armstrong, Joel , Fredrickson, Jeanne , Pak, Evgenia , Tigyi, Kristof , Kremitzki, Milinn , Markovic, Christopher , Maduro, Valerie , Dutra, Amalia , Bouffard, Gerard G. , Chang, Alexander M. , Hansen, Nancy F. , Wilfert, Amy B. , Thibaud-Nissen, Françoise , Schmitt, Anthony D. , Belton, Jon-Matthew , Selvaraj, Siddarth , Dennis, Megan Y. , Soto, Daniela C. , Sahasrabudhe, Ruta , Kaya, Gulhan , Quick, Josh , Loman, Nicholas J. , Holmes, Nadine , Loose, Matthew , Surti, Urvashi , Risques, Rosa ana , Graves Lindsay, Tina A. , Fulton, Robert , Hall, Ira , Paten, Benedict , Howe, Kerstin , Timp, Winston , Young, Alice , Mullikin, James C. , Pevzner, Pavel A. , Gerton, Jennifer L. , Sullivan, Beth A. , Eichler, Evan E. and Phillippy, Adam M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
After two decades of improvements, the current human reference genome (GRCh38) is the most accurate and complete vertebrate genome ever produced. However, no single chromosome has been finished end to end, and hundreds of unresolved gaps persist
1
,
2
. Here we present a human genome assembly that surpasses the continuity of GRCh38
2...
Alternative Titles
Full title
Telomere-to-telomere assembly of a complete human X chromosome
Authors, Artists and Contributors
Author / Creator
Koren, Sergey
Rhie, Arang
Vollger, Mitchell R.
Gershman, Ariel
Bzikadze, Andrey
Brooks, Shelise
Howe, Edmund
Porubsky, David
Logsdon, Glennis A.
Schneider, Valerie A.
Potapova, Tamara
Wood, Jonathan
Chow, William
Armstrong, Joel
Fredrickson, Jeanne
Pak, Evgenia
Tigyi, Kristof
Kremitzki, Milinn
Markovic, Christopher
Maduro, Valerie
Dutra, Amalia
Bouffard, Gerard G.
Chang, Alexander M.
Hansen, Nancy F.
Wilfert, Amy B.
Thibaud-Nissen, Françoise
Schmitt, Anthony D.
Belton, Jon-Matthew
Selvaraj, Siddarth
Dennis, Megan Y.
Soto, Daniela C.
Sahasrabudhe, Ruta
Kaya, Gulhan
Quick, Josh
Loman, Nicholas J.
Holmes, Nadine
Loose, Matthew
Surti, Urvashi
Risques, Rosa ana
Graves Lindsay, Tina A.
Fulton, Robert
Hall, Ira
Paten, Benedict
Howe, Kerstin
Timp, Winston
Young, Alice
Mullikin, James C.
Pevzner, Pavel A.
Gerton, Jennifer L.
Sullivan, Beth A.
Eichler, Evan E.
Phillippy, Adam M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7484160
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7484160
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2547-7
