Supplementation of l‐arginine boosts the therapeutic efficacy of anticancer chemoimmunotherapy
Supplementation of l‐arginine boosts the therapeutic efficacy of anticancer chemoimmunotherapy
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Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Myeloid‐derived suppressor cells (MDSCs) play a crucial role in immunosuppression in tumor‐bearing hosts. MDSCs express arginase‐I and indoleamine 2,3‐dioxygenase; they suppress T‐cell function by reducing the levels of l‐arginine and l‐tryptophan, respectively. We examined the anticancer effects of supplementation of these amino acids in CT26 colo...
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Full title
Supplementation of l‐arginine boosts the therapeutic efficacy of anticancer chemoimmunotherapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7484823
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7484823
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ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.14490
