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Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche

Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7490650

Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche

About this item

Full title

Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2020-04, Vol.580 (7804), p.524-529

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The initiation of an intestinal tumour is a probabilistic process that depends on the competition between mutant and normal epithelial stem cells in crypts
1
. Intestinal stem cells are closely associated with a diverse but poorly characterized network of mesenchymal cell types
2
,
3
. However, whether the physiological mesenchyma...

Alternative Titles

Full title

Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7490650

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7490650

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-2166-3

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