Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche
Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche
About this item
Full title
Author / Creator
Roulis, Manolis , Kaklamanos, Aimilios , Schernthanner, Marina , Bielecki, Piotr , Zhao, Jun , Kaffe, Eleanna , Frommelt, Laura-Sophie , Qu, Rihao , Knapp, Marlene S. , Henriques, Ana , Chalkidi, Niki , Koliaraki, Vasiliki , Jiao, Jing , Brewer, J. Richard , Bacher, Maren , Blackburn, Holly N. , Zhao, Xiaoyun , Breyer, Richard M. , Aidinis, Vassilis , Jain, Dhanpat , Su, Bing , Herschman, Harvey R. , Kluger, Yuval , Kollias, George and Flavell, Richard A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The initiation of an intestinal tumour is a probabilistic process that depends on the competition between mutant and normal epithelial stem cells in crypts
1
. Intestinal stem cells are closely associated with a diverse but poorly characterized network of mesenchymal cell types
2
,
3
. However, whether the physiological mesenchyma...
Alternative Titles
Full title
Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche
Authors, Artists and Contributors
Author / Creator
Kaklamanos, Aimilios
Schernthanner, Marina
Bielecki, Piotr
Zhao, Jun
Kaffe, Eleanna
Frommelt, Laura-Sophie
Qu, Rihao
Knapp, Marlene S.
Henriques, Ana
Chalkidi, Niki
Koliaraki, Vasiliki
Jiao, Jing
Brewer, J. Richard
Bacher, Maren
Blackburn, Holly N.
Zhao, Xiaoyun
Breyer, Richard M.
Aidinis, Vassilis
Jain, Dhanpat
Su, Bing
Herschman, Harvey R.
Kluger, Yuval
Kollias, George
Flavell, Richard A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7490650
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7490650
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2166-3