Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation
Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Peptide ligands of class B G-protein-coupled receptors act via a two-step binding process, but the essential mechanisms that link their extracellular binding to intracellular receptor–arrestin interactions are not fully understood. Using NMR, crosslinking coupled to mass spectrometry, signaling experiments and computational approaches on the parath...
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Full title
Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7502484
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7502484
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-020-0567-0