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Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation

Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7502484

Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation

About this item

Full title

Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2020-10, Vol.16 (10), p.1096-1104

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Peptide ligands of class B G-protein-coupled receptors act via a two-step binding process, but the essential mechanisms that link their extracellular binding to intracellular receptor–arrestin interactions are not fully understood. Using NMR, crosslinking coupled to mass spectrometry, signaling experiments and computational approaches on the parath...

Alternative Titles

Full title

Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7502484

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7502484

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-020-0567-0

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