Early evolutionary loss of the lipid A modifying enzyme PagP resulting in innate immune evasion in Y...
Early evolutionary loss of the lipid A modifying enzyme PagP resulting in innate immune evasion in Yersinia pestis
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Immune evasion through membrane remodeling is a hallmark of Yersinia pestis pathogenesis. Yersinia remodels its membrane during its life cycle as it alternates between mammalian hosts (37 °C) and ambient (21 °C to 26 °C) temperatures of the arthropod transmission vector or external environment. This shift in growth temperature induces changes in nu...
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Full title
Early evolutionary loss of the lipid A modifying enzyme PagP resulting in innate immune evasion in Yersinia pestis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7502761
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7502761
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1917504117