Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results...
Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial
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Author / Creator
Brunner, Hermine I , Abud-Mendoza, Carlos , Viola, Diego O , Calvo Penades, Inmaculada , Levy, Deborah , Anton, Jordi , Calderon, Julia E , Chasnyk, Vyacheslav G , Ferrandiz, Manuel A , Keltsev, Vladimir , Paz Gastanaga, Maria E , Shishov, Michael , Boteanu, Alina Lucica , Henrickson, Michael , Bass, Damon , Clark, Kenneth , Hammer, Anne , Ji, Beulah N , Nino, Antonio , Roth, David A , Struemper, Herbert , Wang, Mei-Lun , Martini, Alberto , Lovell, Daniel , Ruperto, Nicolino , Cuttica, Rubén , Silverman, Earl , Miettunen, Paivi , Kawano, Yoshifumi , Takei, Syuji , Iwata, Naomi , Mori, Masaaki , Umebayashi, Hiroaki , Smolewska, Elzbieta , Gazda, Agnieszka , Rutkowska-Sak, Lidia , Ciurtin, Coziana , Ioannou, John , Clinch, Jacqui Georgina , McCann, Liza Jennifer , Baildam, Eileen Marion , Pilkington, Clarissa , Jerath, Rita Sethi , Syed, Reema Hameed , Wahezi, Dawn M , Jung, Lawrence K L and Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG)
Publisher
England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd and European League Against Rheumatism
Subjects
More information
Scope and Contents
Contents
ObjectivesThis ongoing Phase-2, randomised, placebo-controlled, double-blind study evaluated the efficacy, safety and pharmacokinetics of intravenous belimumab in childhood-onset systemic lupus erythematosus (cSLE).MethodsPatients (5 to 17 years) were randomised to belimumab 10 mg/kg intravenous or placebo every 4 weeks, plus standard SLE therapy....
Alternative Titles
Full title
Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial
Authors, Artists and Contributors
Author / Creator
Abud-Mendoza, Carlos
Viola, Diego O
Calvo Penades, Inmaculada
Levy, Deborah
Anton, Jordi
Calderon, Julia E
Chasnyk, Vyacheslav G
Ferrandiz, Manuel A
Keltsev, Vladimir
Paz Gastanaga, Maria E
Shishov, Michael
Boteanu, Alina Lucica
Henrickson, Michael
Bass, Damon
Clark, Kenneth
Hammer, Anne
Ji, Beulah N
Nino, Antonio
Roth, David A
Struemper, Herbert
Wang, Mei-Lun
Martini, Alberto
Lovell, Daniel
Ruperto, Nicolino
Cuttica, Rubén
Silverman, Earl
Miettunen, Paivi
Kawano, Yoshifumi
Takei, Syuji
Iwata, Naomi
Mori, Masaaki
Umebayashi, Hiroaki
Smolewska, Elzbieta
Gazda, Agnieszka
Rutkowska-Sak, Lidia
Ciurtin, Coziana
Ioannou, John
Clinch, Jacqui Georgina
McCann, Liza Jennifer
Baildam, Eileen Marion
Pilkington, Clarissa
Jerath, Rita Sethi
Syed, Reema Hameed
Wahezi, Dawn M
Jung, Lawrence K L
Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG)
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7509523
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7509523
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2020-217101
