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Newsletter articlesFull Text
INTERNATIONAL PATENT: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED , BISWAS, SWETHAJIT , JACKSON, NICOLA A. , PAUL, ELAINE MARIE , STRUEMPER, HERBERT , OPALINSKA, JOANNA FILES APPLICATION...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2020
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ArticlesPeer ReviewedFull Text
Safety, Pharmacokinetics, and Pharmacodynamics of the TLR4 Agonist GSK1795091 in Healthy Individuals: Results from a Randomized, Double-blind, Placebo-controlled, Ascending Dose Study
Author / Creator:Hug, Bruce A ; Matheny, Christopher J ; Burns, Olivia ; Struemper, Herbert ; Wang, Xiaowei ; Washburn, Michael L
Publisher:United States: Elsevier Inc
Journal title:Clinical therapeutics, 2020-08, Vol.42 (8), p.1519-1534.e33
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ArticlesPeer ReviewedFull Text
Population pharmacokinetics of belantamab mafodotin, a BCMA‐targeting agent in patients with relapsed/refractory multiple myeloma
Author / Creator:Rathi, Chetan ; Collins, Jon ; Struemper, Herbert ; Opalinska, Joanna ; Jewell, Roxanne C. ; Ferron‐Brady, Geraldine
Publisher:United States: John Wiley & Sons, Inc
Journal title:CPT: pharmacometrics and systems pharmacology, 2021-08, Vol.10 (8), p.851-863
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ArticlesPeer ReviewedFull Text
Tutorial on Conditional Simulations With a Tumor Size‐Overall Survival Model to Support Oncology Drug Development
Author / Creator:Goulooze, Sebastiaan C. ; Muliaditan, Morris ; Franzese, Richard C. ; Mantero, Alejandro ; Visser, Sandra A. G. ; Melhem, Murad ; Post, Teun M. ; Rathi, Chetan ; Struemper, Herbert
Publisher:United States: John Wiley & Sons, Inc
Journal title:CPT: pharmacometrics and systems pharmacology, 2025-04, Vol.14 (4), p.640-650
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ArticlesPeer ReviewedFull Text
Reductions in circulating B cell subsets and immunoglobulin G levels with long-term belimumab treatment in patients with SLE
Author / Creator:Struemper, Herbert ; Kurtinecz, Milena ; Edwards, Lisa ; Freimuth, William W ; Roth, David A ; Stohl, William
Publisher:England: Lupus Foundation of America
Journal title:Lupus science & medicine, 2022-02, Vol.9 (1), p.e000499
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ArticlesPeer ReviewedFull Text
Longitudinal efficacy and safety modeling and simulation framework to aid dose selection of belantamab mafodotin for patients with multiple myeloma
Author / Creator:Collins, Jon ; van Noort, Martijn ; Rathi, Chetan ; Post, Teun M. ; Struemper, Herbert ; Jewell, Roxanne C. ; Ferron‐Brady, Geraldine
Publisher:United States: John Wiley & Sons, Inc
Journal title:CPT: pharmacometrics and systems pharmacology, 2023-10, Vol.12 (10), p.1411-1424
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ArticlesPeer ReviewedFull Text
Manufacturing‐dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development
Author / Creator:Steeghs, Neeltje ; Hansen, Aaron R. ; Hanna, Glenn J. ; Garralda, Elena ; Park, Haeseong ; Strauss, James ; Adam, Michael ; Campbell, Gossett ; Carver, Jennifer ; Easton, Rachael ; Mays, Katherine ; Skrdla, Peter ; Struemper, Herbert ; Washburn, Michael L. ; Matheny, Christopher ; Piha‐Paul, Sarina A.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2022-11, Vol.15 (11), p.2625-2639
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ArticlesPeer ReviewedFull Text
First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1)
Author / Creator:Postel-Vinay, Sophie ; Lam, Vincent K ; Ros, Willeke ; Bauer, Todd M ; Hansen, Aaron R ; Cho, Daniel C ; Stephen Hodi, F ; Schellens, Jan H M ; Litton, Jennifer K ; Aspeslagh, Sandrine ; Autio, Karen A ; Opdam, Frans L ; McKean, Meredith ; Somaiah, Neeta ; Champiat, Stephane ; Altan, Mehmet ; Spreafico, Anna ; Rahma, Osama ; Paul, Elaine M ; Ahlers, Christoph M ; Zhou, Helen ; Struemper, Herbert ; Gorman, Shelby A ; Watmuff, Maura ; Yablonski, Kaitlin M ; Yanamandra, Niranjan ; Chisamore, Michael J ; Schmidt, Emmett V ; Hoos, Axel ; Marabelle, Aurelien ; Weber, Jeffrey S ; Heymach, John V
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-03, Vol.11 (3), p.e005301
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ArticlesPeer ReviewedFull Text
Population Pharmacokinetic and Pharmacodynamic Analysis of Belimumab Administered Subcutaneously in Healthy Volunteers and Patients with Systemic Lupus Erythematosus
Author / Creator:Struemper, Herbert ; Thapar, Mita ; Roth, David
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2018-06, Vol.57 (6), p.717-728
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ArticlesPeer ReviewedFull Text
Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial
Author / Creator:Brunner, Hermine I ; Abud-Mendoza, Carlos ; Viola, Diego O ; Calvo Penades, Inmaculada ; Levy, Deborah ; Anton, Jordi ; Calderon, Julia E ; Chasnyk, Vyacheslav G ; Ferrandiz, Manuel A ; Keltsev, Vladimir ; Paz Gastanaga, Maria E ; Shishov, Michael ; Boteanu, Alina Lucica ; Henrickson, Michael ; Bass, Damon ; Clark, Kenneth ; Hammer, Anne ; Ji, Beulah N ; Nino, Antonio ; Roth, David A ; Struemper, Herbert ; Wang, Mei-Lun ; Martini, Alberto ; Lovell, Daniel ; Ruperto, Nicolino ; Cuttica, Rubén ; Silverman, Earl ; Miettunen, Paivi ; Kawano, Yoshifumi ; Takei, Syuji ; Iwata, Naomi ; Mori, Masaaki ; Umebayashi, Hiroaki ; Smolewska, Elzbieta ; Gazda, Agnieszka ; Rutkowska-Sak, Lidia ; Ciurtin, Coziana ; Ioannou, John ; Clinch, Jacqui Georgina ; McCann, Liza Jennifer ; Baildam, Eileen Marion ; Pilkington, Clarissa ; Jerath, Rita Sethi ; Syed, Reema Hameed ; Wahezi, Dawn M ; Jung, Lawrence K L
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2020-10, Vol.79 (10), p.1340-1348
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ArticlesPeer ReviewedFull Text
Development of a Joint Tumor Size–Overall Survival Modeling and Simulation Framework Supporting Oncology Development Decision‐Making
Author / Creator:Struemper, Herbert ; Rathi, Chetan ; Muliaditan, Morris ; Goulooze, Sebastiaan C. ; Franzese, Richard C. ; Mantero, Alejandro ; Melhem, Murad ; Post, Teun M. ; Visser, Sandra A. G.
Publisher:United States
Journal title:CPT: pharmacometrics and systems pharmacology, 2025-02
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ArticlesPeer ReviewedFull Text
Evaluation of a novel autoinjector for subcutaneous self-administration of belimumab in systemic lupus erythematosus
Author / Creator:Sheikh, Saira Z. ; Hammer, Anne E. ; Fox, Norma Lynn ; Groark, James ; Struemper, Herbert ; Roth, David ; Gordon, David
Publisher:Germany: Dustri - Verlag Dr. Karl Feistle GmbH & Co. KG
Journal title:International journal of clinical pharmacology and therapeutics, 2016-11, Vol.54 (11), p.914-922
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ArticlesPeer ReviewedFull Text
FRI0181 THE PLUTO STUDY: INTRAVENOUS BELIMUMAB IN CHILDREN WITH SYSTEMIC LUPUS ERYTHEMATOSUS
Author / Creator:Ruperto, Nicolino ; Abud-Mendoza, Carlos ; Viola, Diego O. ; Calvo, Inmaculada ; Levy, Deborah M. ; Gallegos, Julia Calderon ; Ferrandiz, Manuel ; Chasnyk, Vyacheslav ; Keltsev, Vladimir ; Anton, Jordi ; Gastanaga, Maria ; Shishov, Michael ; Boteanu, Alina ; Henrickson, Michael ; Bass, Damon ; Clark, Ken ; Hammer, Anne ; Ji, Beulah ; Nino, Antonio ; Roth, David ; Struemper, Herbert ; Wang, Mei-Lun ; Martini, Alberto ; Lovell, Daniel J ; Brunner, Hermine
Journal title:Annals of the rheumatic diseases, 2019-06, Vol.78, p.764-765
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ArticlesPeer ReviewedFull Text
Methods and strategies for assessing uncontrolled drug–drug interactions in population pharmacokinetic analyses: results from the International Society of Pharmacometrics (ISOP) Working Group
Author / Creator:Bonate, Peter L. ; Ahamadi, Malidi ; Budha, Nageshwar ; de la Peña, Amparo ; Earp, Justin C. ; Hong, Ying ; Karlsson, Mats O. ; Ravva, Patanjali ; Ruiz-Garcia, Ana ; Struemper, Herbert ; Wade, Janet R.
Publisher:New York: Springer US
Journal title:Journal of pharmacokinetics and pharmacodynamics, 2016-04, Vol.43 (2), p.123-135
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INTERNATIONAL PATENT: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED , BISWAS, SWETHAJIT , JACKSON, NICOLA A. , PAUL, ELAINE MARIE , STRUEMPER, HERBERT , OPALINSKA, JOANNA FILES APPLICATION...

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Safety, Pharmacokinetics, and Pharmacodynamics of the TLR4 Agonist GSK1795091 in Healthy Individuals: Results from a Randomized, Double-blind, Placebo-controlled, Ascending Dose Study

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Population pharmacokinetics of belantamab mafodotin, a BCMA‐targeting agent in patients with relapsed/refractory multiple myeloma

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Tutorial on Conditional Simulations With a Tumor Size‐Overall Survival Model to Support Oncology Drug Development

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Reductions in circulating B cell subsets and immunoglobulin G levels with long-term belimumab treatment in patients with SLE

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Longitudinal efficacy and safety modeling and simulation framework to aid dose selection of belantamab mafodotin for patients with multiple myeloma

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Manufacturing‐dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development

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First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1)

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Population Pharmacokinetic and Pharmacodynamic Analysis of Belimumab Administered Subcutaneously in Healthy Volunteers and Patients with Systemic Lupus Erythematosus

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Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial

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Development of a Joint Tumor Size–Overall Survival Modeling and Simulation Framework Supporting Oncology Development Decision‐Making

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Evaluation of a novel autoinjector for subcutaneous self-administration of belimumab in systemic lupus erythematosus

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FRI0181 THE PLUTO STUDY: INTRAVENOUS BELIMUMAB IN CHILDREN WITH SYSTEMIC LUPUS ERYTHEMATOSUS

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Methods and strategies for assessing uncontrolled drug–drug interactions in population pharmacokinetic analyses: results from the International Society of Pharmacometrics (ISOP) Working Group

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