PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers
PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers
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Author / Creator
Liu, Rui , Chen, Youwen , Liu, Guangzhi , Li, Chenxi , Song, Yurong , Cao, Zhiwen , Li, Wen , Hu, Jinghong , Lu, Cheng and Liu, Yuanyan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Multidrug resistance (MDR) is the dominant challenge in the failure of chemotherapy in cancers. Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that spreads intracellular signal cascades and regulates a variety of cellular processes. PI3Ks are considered significant causes of chemoresistance in cancer therapy. Protein kinase B (AKT) is also...
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Full title
PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7515865
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7515865
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-020-02998-6
