Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to ex...
Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Monocyte-derived and tissue-resident macrophages are ontogenetically distinct components of the innate immune system. Assessment of their respective functions in pathology is complicated by changes to the macrophage phenotype during inflammation. Here we find that
Cxcr4
-CreER enables permanent genetic labeling of hematopoietic stem cells (HS...
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Full title
Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7523735
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7523735
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-020-0585-y