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Cyclophilin D-dependent oligodendrocyte mitochondrial ion leak contributes to neonatal white matter...

Cyclophilin D-dependent oligodendrocyte mitochondrial ion leak contributes to neonatal white matter...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7524474

Cyclophilin D-dependent oligodendrocyte mitochondrial ion leak contributes to neonatal white matter injury

About this item

Full title

Cyclophilin D-dependent oligodendrocyte mitochondrial ion leak contributes to neonatal white matter injury

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2020-10, Vol.130 (10), p.5536-5550

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Postnatal failure of oligodendrocyte maturation has been proposed as a cellular mechanism of diffuse white matter injury (WMI) in premature infants. However, the molecular mechanisms for oligodendrocyte maturational failure remain unclear. In neonatal mice and cultured differentiating oligodendrocytes, sublethal intermittent hypoxic (IH) stress act...

Alternative Titles

Full title

Cyclophilin D-dependent oligodendrocyte mitochondrial ion leak contributes to neonatal white matter injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7524474

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7524474

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI133082

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