Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experime...
Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice
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United States: American Society for Clinical Investigation
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Language
English
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United States: American Society for Clinical Investigation
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The tight junction protein claudin-2 is upregulated in disease. Although many studies have linked intestinal barrier loss to local and systemic disease, these have relied on macromolecular probes. In vitro analyses show, however, that these probes cannot be accommodated by size- and charge-selective claudin-2 channels. We sought to define the impac...
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Full title
Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7524482
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7524482
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI138697
