3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing
3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
There is a need for methods that can image chromosomes with genome-wide coverage, as well as greater genomic and optical resolution. We introduce OligoFISSEQ, a suite of three methods that leverage fluorescence in situ sequencing (FISSEQ) of barcoded Oligopaint probes to enable the rapid visualization of many targeted genomic regions. Applying Olig...
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Full title
3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7537785
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7537785
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ISSN
1548-7091,1548-7105
E-ISSN
1548-7105
DOI
10.1038/s41592-020-0890-0
