Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis
Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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DNA polymerase ζ (Polζ) belongs to the same B-family as high-fidelity replicative polymerases, yet is specialized for the extension reaction in translesion DNA synthesis (TLS). Despite its importance in TLS, the structure of Polζ is unknown. We present cryo-EM structures of the
Saccharomyces
cerevisiae
Polζ holoenzyme in the act of DNA syn...
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Full title
Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7554088
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7554088
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/s41594-020-0476-7
