Bacterial lipopolysaccharide as negative predictor of gemcitabine efficacy in advanced pancreatic ca...
Bacterial lipopolysaccharide as negative predictor of gemcitabine efficacy in advanced pancreatic cancer – translational results from the AIO-PK0104 Phase 3 study
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Background
Gram-negative bacteria mediated gemcitabine resistance in pre-clinical models. We determined if intratumoural lipopolysaccharide (LPS) detection by immunohistochemistry is associated with outcome in advanced pancreatic ductal adenocarcinoma (PDAC) treated with gemcitabine and non-gemcitabine containing 1st-line chemotherapy.
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Bacterial lipopolysaccharide as negative predictor of gemcitabine efficacy in advanced pancreatic cancer – translational results from the AIO-PK0104 Phase 3 study
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7591915
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7591915
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-020-01029-7
