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Activity of Platinum-Based Chemotherapy in Patients With Advanced Prostate Cancer With and Without D...

Activity of Platinum-Based Chemotherapy in Patients With Advanced Prostate Cancer With and Without D...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7593810

Activity of Platinum-Based Chemotherapy in Patients With Advanced Prostate Cancer With and Without DNA Repair Gene Aberrations

Publication information

Publisher

United States: American Medical Association

More information

Scope and Contents

Contents

DNA repair gene aberrations occur in 20% to 30% of patients with castration-resistant prostate cancer (CRPC), and some of these aberrations have been associated with sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition platinum-based treatments. However, previous trials assessing platinum-based treatments in patients with CRPC have mostly i...

Alternative Titles

Full title

Activity of Platinum-Based Chemotherapy in Patients With Advanced Prostate Cancer With and Without DNA Repair Gene Aberrations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7593810

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7593810

Other Identifiers

ISSN

2574-3805

E-ISSN

2574-3805

DOI

10.1001/jamanetworkopen.2020.21692

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