Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease
Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease
About this item
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Author / Creator
Dujardin, Simon , Commins, Caitlin , Lathuiliere, Aurelien , Beerepoot, Pieter , Fernandes, Analiese R. , Kamath, Tarun V. , De Los Santos, Mark B. , Klickstein, Naomi , Corjuc, Diana L. , Corjuc, Bianca T. , Dooley, Patrick M. , Viode, Arthur , Oakley, Derek H. , Moore, Benjamin D. , Mullin, Kristina , Jean-Gilles, Dinorah , Clark, Ryan , Atchison, Kevin , Moore, Renee , Chibnik, Lori B. , Tanzi, Rudolph E. , Frosch, Matthew P. , Serrano-Pozo, Alberto , Elwood, Fiona , Steen, Judith A. , Kennedy, Matthew E. and Hyman, Bradley T.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Alzheimer’s disease (AD) causes unrelenting, progressive cognitive impairments, but its course is heterogeneous, with a broad range of rates of cognitive decline
1
. The spread of tau aggregates (neurofibrillary tangles) across the cerebral cortex parallels symptom severity
2
,
3
. We hypothesized that the kinetics of tau spread m...
Alternative Titles
Full title
Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Commins, Caitlin
Lathuiliere, Aurelien
Beerepoot, Pieter
Fernandes, Analiese R.
Kamath, Tarun V.
De Los Santos, Mark B.
Klickstein, Naomi
Corjuc, Diana L.
Corjuc, Bianca T.
Dooley, Patrick M.
Viode, Arthur
Oakley, Derek H.
Moore, Benjamin D.
Mullin, Kristina
Jean-Gilles, Dinorah
Clark, Ryan
Atchison, Kevin
Moore, Renee
Chibnik, Lori B.
Tanzi, Rudolph E.
Frosch, Matthew P.
Serrano-Pozo, Alberto
Elwood, Fiona
Steen, Judith A.
Kennedy, Matthew E.
Hyman, Bradley T.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7603860
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7603860
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-020-0938-9
