Expression of a novel brain specific isoform of C3G is regulated during development
Expression of a novel brain specific isoform of C3G is regulated during development
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Mice lacking C3G (RapGEF1), a ubiquitously expressed protein essential for neuronal differentiation, show multiple defects in brain development. Function of C3G in neurogenesis is poorly defined. Here, we identify brain specific expression of a novel C3G isoform in mice and humans. This isoform has an insert in the Crk-binding region, generating a...
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Full title
Expression of a novel brain specific isoform of C3G is regulated during development
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7606606
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7606606
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-75813-z
