Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal ca...
Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Wnt signaling dysregulation promotes tumorigenesis in colorectal cancer (CRC). We investigated the role of PTPRF, a receptor-type tyrosine phosphatase, in regulating Wnt signaling in CRC. Knockdown of PTPRF decreased cell proliferation in patient-derived primary colon cancer cells and established CRC cell lines. In addition, the rate of proliferati...
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Full title
Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7606795
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7606795
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-020-01472-z
