Single-molecule visualization of DNA G-quadruplex formation in live cells
Single-molecule visualization of DNA G-quadruplex formation in live cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Substantial evidence now exists to support that formation of DNA G-quadruplexes (G4s) is coupled to altered gene expression. However, approaches that allow us to probe G4s in living cells without perturbing their folding dynamics are required to understand their biological roles in greater detail. Herein, we report a G4-specific fluorescent probe (...
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Full title
Single-molecule visualization of DNA G-quadruplex formation in live cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610488
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610488
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/s41557-020-0506-4