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Single-molecule visualization of DNA G-quadruplex formation in live cells

Single-molecule visualization of DNA G-quadruplex formation in live cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610488

Single-molecule visualization of DNA G-quadruplex formation in live cells

About this item

Full title

Single-molecule visualization of DNA G-quadruplex formation in live cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature chemistry, 2020-09, Vol.12 (9), p.832-837

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Substantial evidence now exists to support that formation of DNA G-quadruplexes (G4s) is coupled to altered gene expression. However, approaches that allow us to probe G4s in living cells without perturbing their folding dynamics are required to understand their biological roles in greater detail. Herein, we report a G4-specific fluorescent probe (...

Alternative Titles

Full title

Single-molecule visualization of DNA G-quadruplex formation in live cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610488

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610488

Other Identifiers

ISSN

1755-4330

E-ISSN

1755-4349

DOI

10.1038/s41557-020-0506-4

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