Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infec...
Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection
About this item
Full title
Author / Creator
Selkrig, Joel , Li, Nan , Hausmann, Annika , Mangan, Matthew S. J. , Zietek, Matylda , Mateus, André , Bobonis, Jacob , Sueki, Anna , Imamura, Haruna , El Debs, Bachir , Sigismondo, Gianluca , Florea, Bogdan I. , Overkleeft, Herman S. , Kopitar-Jerala, Nataša , Turk, Boris , Beltrao, Pedro , Savitski, Mikhail M. , Latz, Eicke , Hardt, Wolf-Dietrich , Krijgsveld, Jeroen and Typas, Athanasios
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The interplay between host and pathogen relies heavily on rapid protein synthesis and accurate protein targeting to ensure pathogen destruction. To gain insight into this dynamic interface, we combined Click chemistry with pulsed stable isotope labelling of amino acids in cell culture to quantify the host proteome response during macrophage infecti...
Alternative Titles
Full title
Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection
Authors, Artists and Contributors
Author / Creator
Li, Nan
Hausmann, Annika
Mangan, Matthew S. J.
Zietek, Matylda
Mateus, André
Bobonis, Jacob
Sueki, Anna
Imamura, Haruna
El Debs, Bachir
Sigismondo, Gianluca
Florea, Bogdan I.
Overkleeft, Herman S.
Kopitar-Jerala, Nataša
Turk, Boris
Beltrao, Pedro
Savitski, Mikhail M.
Latz, Eicke
Hardt, Wolf-Dietrich
Krijgsveld, Jeroen
Typas, Athanasios
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610801
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7610801
Other Identifiers
ISSN
2058-5276
E-ISSN
2058-5276
DOI
10.1038/s41564-020-0736-7
