A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolu...
A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants
About this item
Full title
Author / Creator
Diard, Médéric , Bakkeren, Erik , Lentsch, Verena , Rocker, Andrea , Bekele, Nahimi Amare , Hoces, Daniel , Aslani, Selma , Arnoldini, Markus , Böhi, Flurina , Schumann-Moor, Kathrin , Adamcik, Jozef , Piccoli, Luca , Lanzavecchia, Antonio , Stadtmueller, Beth M. , Donohue, Nicholas , van der Woude, Marjan W. , Hockenberry, Alyson , Viollier, Patrick H. , Falquet, Laurent , Wüthrich, Daniel , Bonfiglio, Ferdinando , Loverdo, Claude , Egli, Adrian , Zandomeneghi, Giorgia , Mezzenga, Raffaele , Holst, Otto , Meier, Beat H. , Hardt, Wolf-Dietrich and Slack, Emma
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The ability of gut bacterial pathogens to escape immunity by antigenic variation—particularly via changes to surface-exposed antigens—is a major barrier to immune clearance
1
. However, not all variants are equally fit in all environments
2
,
3
. It should therefore be possible to exploit such immune escape mechanisms to direct an...
Alternative Titles
Full title
A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants
Authors, Artists and Contributors
Author / Creator
Bakkeren, Erik
Lentsch, Verena
Rocker, Andrea
Bekele, Nahimi Amare
Hoces, Daniel
Aslani, Selma
Arnoldini, Markus
Böhi, Flurina
Schumann-Moor, Kathrin
Adamcik, Jozef
Piccoli, Luca
Lanzavecchia, Antonio
Stadtmueller, Beth M.
Donohue, Nicholas
van der Woude, Marjan W.
Hockenberry, Alyson
Viollier, Patrick H.
Falquet, Laurent
Wüthrich, Daniel
Bonfiglio, Ferdinando
Loverdo, Claude
Egli, Adrian
Zandomeneghi, Giorgia
Mezzenga, Raffaele
Holst, Otto
Meier, Beat H.
Hardt, Wolf-Dietrich
Slack, Emma
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7611113
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7611113
Other Identifiers
ISSN
2058-5276
E-ISSN
2058-5276
DOI
10.1038/s41564-021-00911-1
