Structure of pathological TDP-43 filaments from ALS with FTLD
Structure of pathological TDP-43 filaments from ALS with FTLD
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The abnormal aggregation of TAR DNA-binding protein 43 kDa (TDP-43) in neurons and glia is the defining pathological hallmark of the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and multiple forms of frontotemporal lobar degeneration (FTLD)
1
,
2
. It is also common in other diseases, including Alzheimer’s and Parkinson...
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Structure of pathological TDP-43 filaments from ALS with FTLD
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7612255
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7612255
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ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-021-04199-3