The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia
The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia
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Publisher
United States: American Association for the Advancement of Science
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Language
English
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Publisher
United States: American Association for the Advancement of Science
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Contents
Body temperature homeostasis is critical for survival and requires precise regulation by the nervous system. The hypothalamus serves as the principal thermostat that detects and regulates internal temperature. We demonstrate that the ion channel TRPM2 [of the transient receptor potential (TRP) channel family] is a temperature sensor in a subpopulat...
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Full title
The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7612276
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7612276
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aaf7537
