New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive...
New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Oligodendrocytes that survive demyelination can remyelinate, including in multiple sclerosis (MS), but how they do so is unclear. In this study, using zebrafish, we found that surviving oligodendrocytes make few new sheaths and frequently mistarget new myelin to neuronal cell bodies, a pathology we also found in MS. In contrast, oligodendrocytes ge...
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New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7612594
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7612594
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-021-01009-x
