Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals
Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Ferroptosis is a type of cell death caused by radical-driven lipid peroxidation, leading to membrane damage and rupture. Here we show that enzymatically produced sulfane sulfur (S
0
) species, specifically hydropersulfides, scavenge endogenously generated free radicals and, thereby, suppress lipid peroxidation and ferroptosis. By providing su...
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Full title
Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7613997
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7613997
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-022-01145-w
