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Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive...

Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7616283

Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis

About this item

Full title

Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis

Publisher

England: Nature Publishing Group

Journal title

Nature Cardiovascular Research, 2024-02, Vol.3 (2), p.221-242

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

Scope and Contents

Contents

CCL17 is produced by conventional dendritic cells, signals through CCR4 on regulatory T (T
reg
) cells and drives atherosclerosis by suppressing T
reg
functions through yet undefined mechanisms. Here we show that conventional dendritic cells from CCL17-deficient mice display a pro-tolerogenic phenotype and transcriptome that is not phen...

Alternative Titles

Full title

Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7616283

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7616283

Other Identifiers

ISSN

2731-0590

E-ISSN

2731-0590

DOI

10.1038/s44161-023-00413-9

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