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ArticlesPeer ReviewedFull Text
Molecular roles and function of circular RNAs in eukaryotic cells
Author / Creator:Holdt, Lesca M. ; Kohlmaier, Alexander ; Teupser, Daniel
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2018-03, Vol.75 (6), p.1071-1098
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Revisiting biomarker discovery by plasma proteomics
Author / Creator:Geyer, Philipp E ; Holdt, Lesca M ; Teupser, Daniel ; Mann, Matthias
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2017-09, Vol.13 (9), p.942-n/a
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Inflammatory Cytokines in General and Central Obesity and Modulating Effects of Physical Activity
Author / Creator:Schmidt, Frank M. ; Weschenfelder, Julia ; Sander, Christian ; Minkwitz, Juliane ; Thormann, Julia ; Chittka, Tobias ; Mergl, Roland ; Kirkby, Kenneth C. ; Faßhauer, Mathias ; Stumvoll, Michael ; Holdt, Lesca M. ; Teupser, Daniel ; Hegerl, Ulrich ; Himmerich, Hubertus
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-03, Vol.10 (3), p.e0121971-e0121971
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Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks
Author / Creator:Holdt, Lesca M. ; Hoffmann, Steve ; Sass, Kristina ; Langenberger, David ; Scholz, Markus ; Krohn, Knut ; Finstermeier, Knut ; Stahringer, Anika ; Wilfert, Wolfgang ; Beutner, Frank ; Gielen, Stephan ; Schuler, Gerhard ; Gäbel, Gabor ; Bergert, Hendrik ; Bechmann, Ingo ; Stadler, Peter F. ; Thiery, Joachim ; Teupser, Daniel
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2013-07, Vol.9 (7), p.e1003588
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Plasma Proteome Profiling to detect and avoid sample‐related biases in biomarker studies
Author / Creator:Geyer, Philipp E ; Voytik, Eugenia ; Treit, Peter V ; Doll, Sophia ; Kleinhempel, Alisa ; Niu, Lili ; Müller, Johannes B ; Buchholtz, Marie‐Luise ; Bader, Jakob M ; Teupser, Daniel ; Holdt, Lesca M ; Mann, Matthias
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2019-11, Vol.11 (11), p.e10427-n/a
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Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans
Author / Creator:Holdt, Lesca M. ; Stahringer, Anika ; Sass, Kristina ; Pichler, Garwin ; Kulak, Nils A. ; Wilfert, Wolfgang ; Kohlmaier, Alexander ; Herbst, Andreas ; Northoff, Bernd H. ; Nicolaou, Alexandros ; Gäbel, Gabor ; Beutner, Frank ; Scholz, Markus ; Thiery, Joachim ; Musunuru, Kiran ; Krohn, Knut ; Mann, Matthias ; Teupser, Daniel
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-08, Vol.7 (1), p.12429-12429, Article 12429
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Preanalytical Conditions and DNA Isolation Methods Affect Telomere Length Quantification in Whole Blood
Author / Creator:Tolios, Alexander ; Teupser, Daniel ; Holdt, Lesca M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-12, Vol.10 (12), p.e0143889-e0143889
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Whole genome sequencing of Brucella melitensis isolated from 57 patients in Germany reveals high diversity in strains from Middle East
Author / Creator:Georgi, Enrico ; Walter, Mathias C. ; Pfalzgraf, Marie-Theres ; Northoff, Bernd H. ; Holdt, Lesca M. ; Scholz, Holger C. ; Zoeller, Lothar ; Zange, Sabine ; Antwerpen, Markus H.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-04, Vol.12 (4), p.e0175425-e0175425
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Comparison of Whole Blood RNA Preservation Tubes and Novel Generation RNA Extraction Kits for Analysis of mRNA and MiRNA Profiles
Author / Creator:Häntzsch, Madlen ; Tolios, Alexander ; Beutner, Frank ; Nagel, Dorothea ; Thiery, Joachim ; Teupser, Daniel ; Holdt, Lesca M.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-12, Vol.9 (12), p.e113298-e113298
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Late-pregnancy dysglycemia in obese pregnancies after negative testing for gestational diabetes and risk of future childhood overweight: An interim analysis from a longitudinal mother–child cohort stu...
Author / Creator:Gomes, Delphina ; von Kries, Rüdiger ; Delius, Maria ; Mansmann, Ulrich ; Nast, Martha ; Stubert, Martina ; Langhammer, Lena ; Haas, Nikolaus A. ; Netz, Heinrich ; Obermeier, Viola ; Kuhle, Stefan ; Holdt, Lesca M. ; Teupser, Daniel ; Hasbargen, Uwe ; Roscher, Adelbert A. ; Ensenauer, Regina
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2018-10, Vol.15 (10), p.e1002681-e1002681
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ArticlesPeer ReviewedFull Text
A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection
Author / Creator:Hoffmann, Steve ; Otto, Christian ; Doose, Gero ; Tanzer, Andrea ; Langenberger, David ; Christ, Sabina ; Kunz, Manfred ; Holdt, Lesca M ; Teupser, Daniel ; Hackermüller, Jörg ; Stadler, Peter F
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology (Online Edition), 2014-02, Vol.15 (2), p.R34-R34, Article R34
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High‐resolution serum proteome trajectories in COVID‐19 reveal patient‐specific seroconversion
Author / Creator:Geyer, Philipp E ; Arend, Florian M ; Doll, Sophia ; Louiset, Marie‐Luise ; Virreira Winter, Sebastian ; Müller‐Reif, Johannes B ; Torun, Furkan M ; Weigand, Michael ; Eichhorn, Peter ; Bruegel, Mathias ; Strauss, Maximilian T ; Holdt, Lesca M ; Mann, Matthias ; Teupser, Daniel
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2021-08, Vol.13 (8), p.e14167-n/a
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Variability of linezolid concentrations after standard dosing in critically ill patients: a prospective observational study
Author / Creator:Zoller, Michael ; Maier, Barbara ; Hornuss, Cyrill ; Neugebauer, Christina ; Döbbeler, Gundula ; Nagel, Dorothea ; Holdt, Lesca Miriam ; Bruegel, Mathias ; Weig, Thomas ; Grabein, Béatrice ; Frey, Lorenz ; Teupser, Daniel ; Vogeser, Michael ; Zander, Johannes
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2014-07, Vol.18 (4), p.R148-R148, Article R148
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ArticlesPeer ReviewedFull Text
Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer
Author / Creator:Bernhart, Stephan H. ; Kretzmer, Helene ; Holdt, Lesca M. ; Jühling, Frank ; Ammerpohl, Ole ; Bergmann, Anke K. ; Northoff, Bernd H. ; Doose, Gero ; Siebert, Reiner ; Stadler, Peter F. ; Hoffmann, Steve
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-11, Vol.6 (1), p.37393-37393, Article 37393
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Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice
Author / Creator:Spix, Barbara ; Butz, Elisabeth S. ; Chen, Cheng-Chang ; Rosato, Anna Scotto ; Tang, Rachel ; Jeridi, Aicha ; Kudrina, Veronika ; Plesch, Eva ; Wartenberg, Philipp ; Arlt, Elisabeth ; Briukhovetska, Daria ; Ansari, Meshal ; Günsel, Gizem Günes ; Conlon, Thomas M. ; Wyatt, Amanda ; Wetzel, Sandra ; Teupser, Daniel ; Holdt, Lesca M. ; Ectors, Fabien ; Boekhoff, Ingrid ; Boehm, Ulrich ; García-Añoveros, Jaime ; Saftig, Paul ; Giera, Martin ; Kobold, Sebastian ; Schiller, Herbert B. ; Zierler, Susanna ; Gudermann, Thomas ; Wahl-Schott, Christian ; Bracher, Franz ; Yildirim, Ali Önder ; Biel, Martin ; Grimm, Christian
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-01, Vol.13 (1), p.318-18, Article 318
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Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood
Author / Creator:Burkhardt, Ralph ; Kirsten, Holger ; Beutner, Frank ; Holdt, Lesca M. ; Gross, Arnd ; Teren, Andrej ; Tönjes, Anke ; Becker, Susen ; Krohn, Knut ; Kovacs, Peter ; Stumvoll, Michael ; Teupser, Daniel ; Thiery, Joachim ; Ceglarek, Uta ; Scholz, Markus
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-09, Vol.11 (9), p.e1005510-e1005510
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SARS-CoV-2 antibody immunoassays in serial samples reveal earlier seroconversion in acutely ill COVID-19 patients developing ARDS
Author / Creator:Buchholtz, Marie-Luise ; Arend, Florian M. ; Eichhorn, Peter ; Weigand, Michael ; Kleinhempel, Alisa ; Häusler, Kurt ; Bruegel, Mathias ; Holdt, Lesca M. ; Teupser, Daniel
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-05, Vol.16 (5), p.e0251587-e0251587
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High susceptibility to fatty liver disease in two-pore channel 2-deficient mice
Author / Creator:Grimm, Christian ; Holdt, Lesca M. ; Chen, Cheng-Chang ; Hassan, Sami ; Müller, Christoph ; Jörs, Simone ; Cuny, Hartmut ; Kissing, Sandra ; Schröder, Bernd ; Butz, Elisabeth ; Northoff, Bernd ; Castonguay, Jan ; Luber, Christian A. ; Moser, Markus ; Spahn, Saskia ; Lüllmann-Rauch, Renate ; Fendel, Christina ; Klugbauer, Norbert ; Griesbeck, Oliver ; Haas, Albert ; Mann, Matthias ; Bracher, Franz ; Teupser, Daniel ; Saftig, Paul ; Biel, Martin ; Wahl-Schott, Christian
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-08, Vol.5 (1), p.4699, Article 4699
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Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells
Author / Creator:Plesch, Eva ; Chen, Cheng-Chang ; Butz, Elisabeth ; Scotto Rosato, Anna ; Krogsaeter, Einar K ; Yinan, Hua ; Bartel, Karin ; Keller, Marco ; Robaa, Dina ; Teupser, Daniel ; Holdt, Lesca M ; Vollmar, Angelika M ; Sippl, Wolfgang ; Puertollano, Rosa ; Medina, Diego ; Biel, Martin ; Wahl-Schott, Christian ; Bracher, Franz ; Grimm, Christian
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2018-11, Vol.7
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Non-invasive detection of iron deficiency by fluorescence measurement of erythrocyte zinc protoporphyrin in the lip
Author / Creator:Hennig, Georg ; Homann, Christian ; Teksan, Ilknur ; Hasbargen, Uwe ; Hasmüller, Stephan ; Holdt, Lesca M. ; Khaled, Nadia ; Sroka, Ronald ; Stauch, Thomas ; Stepp, Herbert ; Vogeser, Michael ; Brittenham, Gary M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-02, Vol.7 (1), p.10776-10776, Article 10776
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Molecular roles and function of circular RNAs in eukaryotic cells

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Revisiting biomarker discovery by plasma proteomics

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Inflammatory Cytokines in General and Central Obesity and Modulating Effects of Physical Activity

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Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks

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Plasma Proteome Profiling to detect and avoid sample‐related biases in biomarker studies

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Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans

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Preanalytical Conditions and DNA Isolation Methods Affect Telomere Length Quantification in Whole Blood

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Whole genome sequencing of Brucella melitensis isolated from 57 patients in Germany reveals high diversity in strains from Middle East

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Comparison of Whole Blood RNA Preservation Tubes and Novel Generation RNA Extraction Kits for Analysis of mRNA and MiRNA Profiles

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Late-pregnancy dysglycemia in obese pregnancies after negative testing for gestational diabetes and risk of future childhood overweight: An interim analysis from a longitudinal mother–child cohort stu...

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A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection

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High‐resolution serum proteome trajectories in COVID‐19 reveal patient‐specific seroconversion

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Variability of linezolid concentrations after standard dosing in critically ill patients: a prospective observational study

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Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer

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Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

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Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood

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SARS-CoV-2 antibody immunoassays in serial samples reveal earlier seroconversion in acutely ill COVID-19 patients developing ARDS

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High susceptibility to fatty liver disease in two-pore channel 2-deficient mice

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Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells

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Non-invasive detection of iron deficiency by fluorescence measurement of erythrocyte zinc protoporphyrin in the lip

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