A protein assembly mediates Xist localization and gene silencing
A protein assembly mediates Xist localization and gene silencing
About this item
Full title
Author / Creator
Pandya-Jones, Amy , Markaki, Yolanda , Serizay, Jacques , Chitiashvili, Tsotne , Mancia Leon, Walter R. , Damianov, Andrey , Chronis, Constantinos , Papp, Bernadett , Chen, Chun-Kan , McKee, Robin , Wang, Xiao-Jun , Chau, Anthony , Sabri, Shan , Leonhardt, Heinrich , Zheng, Sika , Guttman, Mitchell , Black, Douglas. L. and Plath, Kathrin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Nuclear compartments have diverse roles in regulating gene expression, yet the molecular forces and components that drive compartment formation remain largely unclear
1
. The long non-coding RNA
Xist
establishes an intra-chromosomal compartment by localizing at a high concentration in a territory spatially close to its transcription loc...
Alternative Titles
Full title
A protein assembly mediates Xist localization and gene silencing
Authors, Artists and Contributors
Author / Creator
Markaki, Yolanda
Serizay, Jacques
Chitiashvili, Tsotne
Mancia Leon, Walter R.
Damianov, Andrey
Chronis, Constantinos
Papp, Bernadett
Chen, Chun-Kan
McKee, Robin
Wang, Xiao-Jun
Chau, Anthony
Sabri, Shan
Leonhardt, Heinrich
Zheng, Sika
Guttman, Mitchell
Black, Douglas. L.
Plath, Kathrin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7644664
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7644664
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2703-0
