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The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer’s disease

The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7666300

The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer’s disease

About this item

Full title

The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer’s disease

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2020-12, Vol.140 (6), p.811-830

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Alzheimer’s disease (AD) is characterized by amyloid-beta (Aβ) deposits, which come in myriad morphologies with varying clinical relevance. Previously, we observed an atypical Aβ deposit, referred to as the coarse-grained plaque. In this study, we evaluate the plaque’s association with clinical disease and perform in-depth immunohistochemical and m...

Alternative Titles

Full title

The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7666300

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7666300

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-020-02198-8

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