The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer’s disease
The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer’s disease
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Full title
Author / Creator
Boon, Baayla D. C. , Bulk, Marjolein , Jonker, Allert J. , Morrema, Tjado H. J. , van den Berg, Emma , Popovic, Marko , Walter, Jochen , Kumar, Sathish , van der Lee, Sven J. , Holstege, Henne , Zhu, Xiaoyue , Van Nostrand, William E. , Natté, Remco , van der Weerd, Louise , Bouwman, Femke H. , van de Berg, Wilma D. J. , Rozemuller, Annemieke J. M. and Hoozemans, Jeroen J. M.
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Alzheimer’s disease (AD) is characterized by amyloid-beta (Aβ) deposits, which come in myriad morphologies with varying clinical relevance. Previously, we observed an atypical Aβ deposit, referred to as the coarse-grained plaque. In this study, we evaluate the plaque’s association with clinical disease and perform in-depth immunohistochemical and m...
Alternative Titles
Full title
The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Bulk, Marjolein
Jonker, Allert J.
Morrema, Tjado H. J.
van den Berg, Emma
Popovic, Marko
Walter, Jochen
Kumar, Sathish
van der Lee, Sven J.
Holstege, Henne
Zhu, Xiaoyue
Van Nostrand, William E.
Natté, Remco
van der Weerd, Louise
Bouwman, Femke H.
van de Berg, Wilma D. J.
Rozemuller, Annemieke J. M.
Hoozemans, Jeroen J. M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7666300
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7666300
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-020-02198-8