PERK participates in cardiac valve development via fatty acid oxidation and endocardial-mesenchymal...
PERK participates in cardiac valve development via fatty acid oxidation and endocardial-mesenchymal transformation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Protein kinase R-like endoplasmic reticulum kinase (PERK) is one of the endoplasmic reticulum (ER) stress sensors.
PERK
loss-of-function mutations are known to cause Wolcott–Rallison syndrome. This disease is characterized by early-onset diabetes mellitus, skeletal dysplasia, and cardiac valve malformation. To understand the role of PERK in v...
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Full title
PERK participates in cardiac valve development via fatty acid oxidation and endocardial-mesenchymal transformation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7674462
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7674462
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-77199-4
