FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senesc...
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16INK4a increase
About this item
Full title
Author / Creator
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States) , Voisin, Jessica , Farina, Francesca , Naphade, Swati , Fontaine, Morgane , Tshilenge, Kizito‐Tshitoko , Galicia Aguirre, Carlos , Lopez‐Ramirez, Alejandro , Dancourt, Julia , Ginisty, Aurélie , Sasidharan Nair, Satish , Lakshika Madushani, Kuruwitage , Zhang, Ningzhe , Lejeune, François‐Xavier , Verny, Marc , Campisi, Judith , Ellerby, Lisa M. and Neri, Christian
Publisher
London: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
London: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Neurodegenerative diseases (ND) have been linked to the critical process in aging—cellular senescence. However, the temporal dynamics of cellular senescence in ND conditions is unresolved. Here, we show senescence features develop in human Huntington's disease (HD) neural stem cells (NSCs) and medium spiny neurons (MSNs), including the increase of...
Alternative Titles
Full title
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16INK4a increase
Authors, Artists and Contributors
Author / Creator
Voisin, Jessica
Farina, Francesca
Naphade, Swati
Fontaine, Morgane
Tshilenge, Kizito‐Tshitoko
Galicia Aguirre, Carlos
Lopez‐Ramirez, Alejandro
Dancourt, Julia
Ginisty, Aurélie
Sasidharan Nair, Satish
Lakshika Madushani, Kuruwitage
Zhang, Ningzhe
Lejeune, François‐Xavier
Verny, Marc
Campisi, Judith
Ellerby, Lisa M.
Neri, Christian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7681055
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7681055
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.13226
