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Preferential Gq signaling in diabetes: an electrical switch in incretin action and in diabetes progr...

Preferential Gq signaling in diabetes: an electrical switch in incretin action and in diabetes progr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7685717

Preferential Gq signaling in diabetes: an electrical switch in incretin action and in diabetes progression?

About this item

Full title

Preferential Gq signaling in diabetes: an electrical switch in incretin action and in diabetes progression?

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2020-12, Vol.130 (12), p.6235-6237

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Patients with type 2 diabetes (T2D) fail to secrete insulin in response to increased glucose levels that occur with eating. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are two incretins secreted from gastrointestinal cells that amplify insulin secretion when glucose is high. In this issue of the JCI, Oduor...

Alternative Titles

Full title

Preferential Gq signaling in diabetes: an electrical switch in incretin action and in diabetes progression?

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7685717

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7685717

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/jci143199

How to access this item