Proton-driven transformable nanovaccine for cancer immunotherapy
Proton-driven transformable nanovaccine for cancer immunotherapy
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Full title
Author / Creator
Gong, Ningqiang , Zhang, Yuxuan , Teng, Xucong , Wang, Yongchao , Huo, Shuaidong , Qing, Guangchao , Ni, Qiankun , Li, Xianlei , Wang, Jinjin , Ye, Xiaoxia , Zhang, Tingbin , Chen, Shizhu , Wang, Yongji , Yu, Jie , Wang, Paul C. , Gan, Yaling , Zhang, Jinchao , Mitchell, Michael J. , Li, Jinghong and Liang, Xing-Jie
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Cancer vaccines hold great promise for improved cancer treatment. However, endosomal trapping and low immunogenicity of tumour antigens usually limit the efficiency of vaccination strategies. Here, we present a proton-driven nanotransformer-based vaccine, comprising a polymer–peptide conjugate-based nanotransformer and loaded antigenic peptide. The...
Alternative Titles
Full title
Proton-driven transformable nanovaccine for cancer immunotherapy
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7719078
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7719078
Other Identifiers
ISSN
1748-3387
E-ISSN
1748-3395
DOI
10.1038/s41565-020-00782-3