TAT-RasGAP317-326 kills cells by targeting inner-leaflet–enriched phospholipids
TAT-RasGAP317-326 kills cells by targeting inner-leaflet–enriched phospholipids
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Publisher
Washington: National Academy of Sciences
Journal title
Language
English
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Publisher
Washington: National Academy of Sciences
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Scope and Contents
Contents
TAT-RasGAP317–326 is a cell-penetrating peptide-based construct with anticancer and antimicrobial activities. This peptide kills a subset of cancer cells in a manner that does not involve known programmed cell death pathways. Here we have elucidated the mode of action allowing TAT-RasGAP317–326 to kill cells. This peptide binds and disrupts artific...
Alternative Titles
Full title
TAT-RasGAP317-326 kills cells by targeting inner-leaflet–enriched phospholipids
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7749316
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7749316
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2014108117
