Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and It...
Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis
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Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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(IRX) encodes members of homeodomain containing genes which are involved in development and differentiation. Since it has been reported that the
gene is localized in a lung cancer susceptibility locus, the epigenetic regulation and function of IRX1 was investigated in lung carcinogenesis. We observed frequent hypermethylation of the
promoter...
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Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7760495
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7760495
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ISSN
2072-6694
E-ISSN
2072-6694
DOI
10.3390/cancers12123528
