Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mi...
Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD
About this item
Full title
Author / Creator
Benjamin, John T , Plosa, Erin J , Sucre, Jennifer Ms , van der Meer, Riet , Dave, Shivangi , Gutor, Sergey , Nichols, David S , Gulleman, Peter M , Jetter, Christopher S , Han, Wei , Xin, Matthew , Dinella, Peter C , Catanzarite, Ashley , Kook, Seunghyi , Dolma, Kalsang , Lal, Charitharth V , Gaggar, Amit , Blalock, J Edwin , Newcomb, Dawn C , Richmond, Bradley W , Kropski, Jonathan A , Young, Lisa R , Guttentag, Susan H and Blackwell, Timothy S
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Emerging evidence indicates that early life events can increase the risk for developing chronic obstructive pulmonary disease (COPD). Using an inducible transgenic mouse model for NF-κB activation in the airway epithelium, we found that a brief period of inflammation during the saccular stage (P3-P5) but not alveolar stage (P10-P12) of lung develop...
Alternative Titles
Full title
Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD
Authors, Artists and Contributors
Author / Creator
Plosa, Erin J
Sucre, Jennifer Ms
van der Meer, Riet
Dave, Shivangi
Gutor, Sergey
Nichols, David S
Gulleman, Peter M
Jetter, Christopher S
Han, Wei
Xin, Matthew
Dinella, Peter C
Catanzarite, Ashley
Kook, Seunghyi
Dolma, Kalsang
Lal, Charitharth V
Gaggar, Amit
Blalock, J Edwin
Newcomb, Dawn C
Richmond, Bradley W
Kropski, Jonathan A
Young, Lisa R
Guttentag, Susan H
Blackwell, Timothy S
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7773387
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7773387
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI139481
