Widespread occurrence of the droplet state of proteins in the human proteome
Widespread occurrence of the droplet state of proteins in the human proteome
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
A wide range of proteins have been reported to condensate into a dense liquid phase, forming a reversible droplet state. Failure in the control of the droplet state can lead to the formation of the more stable amyloid state, which is often disease-related. These observations prompt the question of how many proteins can undergo liquid–liquid phase s...
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Full title
Widespread occurrence of the droplet state of proteins in the human proteome
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7777240
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7777240
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2007670117