High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genom...
High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing
About this item
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Publisher
Singapore: Springer Singapore
Journal title
Language
English
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Publisher
Singapore: Springer Singapore
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Scope and Contents
Contents
DNA replication stress, a feature of human cancers, often leads to instability at specific genomic loci, such as the common fragile sites (CFSs). Cells experiencing DNA replication stress may also exhibit mitotic DNA synthesis (MiDAS). To understand the physiological function of MiDAS and its relationship to CFSs, we mapped, at high resolution, the...
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Full title
High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7784693
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7784693
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/s41422-020-0358-x
