Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, fun...
Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains
About this item
Full title
Author / Creator
Vaillant-Beuchot, Loan , Mary, Arnaud , Pardossi-Piquard, Raphaëlle , Bourgeois, Alexandre , Lauritzen, Inger , Eysert, Fanny , Kinoshita, Paula Fernanda , Cazareth, Julie , Badot, Céline , Fragaki, Konstantina , Bussiere, Renaud , Martin, Cécile , Mary, Rosanna , Bauer, Charlotte , Pagnotta, Sophie , Paquis-Flucklinger, Véronique , Buée-Scherrer, Valérie , Buée, Luc , Lacas-Gervais, Sandra , Checler, Frédéric and Chami, Mounia
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Several lines of recent evidence indicate that the amyloid precursor protein-derived C-terminal fragments (APP-CTFs) could correspond to an etiological trigger of Alzheimer’s disease (AD) pathology. Altered mitochondrial homeostasis is considered an early event in AD development. However, the specific contribution of APP-CTFs to mitochondrial struc...
Alternative Titles
Full title
Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains
Authors, Artists and Contributors
Author / Creator
Mary, Arnaud
Pardossi-Piquard, Raphaëlle
Bourgeois, Alexandre
Lauritzen, Inger
Eysert, Fanny
Kinoshita, Paula Fernanda
Cazareth, Julie
Badot, Céline
Fragaki, Konstantina
Bussiere, Renaud
Martin, Cécile
Mary, Rosanna
Bauer, Charlotte
Pagnotta, Sophie
Paquis-Flucklinger, Véronique
Buée-Scherrer, Valérie
Buée, Luc
Lacas-Gervais, Sandra
Checler, Frédéric
Chami, Mounia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7785558
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7785558
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-020-02234-7
